漂亮101皮膚科診所

1. Paradoxical psoriasis is becoming a readily recognized side effect of biologics therapy, occurring in approximately 2–5% of patients.

2. Paradoxical psoriasis showed pustulosis, prominent scalp involvement with alopecia, or erythroderma,  due to a pleomorphic interferon response.

3. Paradoxical psoriasis severity is associated with the use of adalimumab and is more common in older patients.

 

J Am Acad Dermatol 2022 Jun 16;[EPub Ahead of Print]

Predictors of Severity in Paradoxical Psoriasis from Biologic Therapies: A Systematic Review